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Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization

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It upregulates full-length PINK1 protein expression and enhances Parkin Ser65 phosphorylation in a time-dependent manner in Parkin-expressing HeLa cells

doi: 10.1186/s12979-019-0145-z 123 van PasselM

Applying an ice cube or cold pack to the injection site for 30 to 60 seconds before injecting numbs the area slightly

for symptoms of a serious allergic reaction